This module deals with statistics-based QSAR methods that correlate activities of target-drug interactions with various molecular descriptors.
1.Nucleic acids:Nucleacid bases, Nucleosides, nucleotides, structure of DNA, RNA and its classifications, Replication of DNA, transcription, transalation and Protein Biosynthesis. DNA finger printing Techniques, Introduction to Recombinant DNA technology. Genetic code, gene therapy (basic concept only), PCR. Chemical Synthesis of Nucleotides, Restriction enzymes. Chemistry of ATP,ADP and AMP.
Buffer in pharmaceutical and biological system, pH, the buffer equation (Henderson Hesselbach), Buffer calculations, three important buffer systems in human body, buffer capacity, osmotic pressure and tonicity, pharmaceutical buffers, preparations of pharmaceutical buffer solutions.
The course covers the pharmacology of chemotherapeutic agents and drugs acting on the cardiovascular system.
Here we discuss the construction of ring systems and Reterosynthesis.
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